Channing Der awarded NCI grant to pursue drug discovery
Channing J. Der, PhD, UNC Lineberger member and Kenan Distinguished Professor in the Department of Pharmacology at the UNC School of Medicine, was awarded a five-year NIH R01 grant entitled “Biological Activity of RAS Oncogenes”. This grant will support his studies to pursue drug discovery for novel was to target “undruggable” KRAS by targeting instead the MYC oncogene. This project includes collaborators from the Lineberger, including Drs. Chad Pecot, Adrienne Cox and Lee Graves.
Dr. Aaron Hobbs’ research project, titled “K-Ras mutant-specific vulnerabilities for novel pancreatic cancer therapies”, involves the search for the long-elusive anti-KRAS drug for pancreatic cancer treatment.
Dr. Angelina Vaseva’s project, entitled “Targeting Myc in Mutant KRAS-Dependent Pancreatic Ductal Adenocarcinoma,” will pursue the MYC oncogene as a novel direction to develop a novel therapeutic strategy for pancreatic cancer.