A research team led by Drs. Adrienne D. Cox and Channing J. Der (members of the UNC Lineberger Program in Molecular Therapeutics) is one of the first recipients of an NCI U01 grant on New Approaches to Synthetic Lethality for Mutant KRas-Dependent Cancers. Their team, which also includes Drs. Ben Major at UNC, Kris Wood at Duke and Krister Wennerberg at FIMM, will pursue novel genetic screens to search for the long-elusive effective anti-KRAS cancer treatment.
They are founding members of the RAS Synthetic Lethal Network, together with research teams from Stanford, Memorial Sloan-Kettering Cancer Center, Harvard Medical School, MIT, and the Frederick National Laboratory RAS Initiative. The UNC Lineberger team will be supported by a four-year grant of $2,134,000.