Bouzahzah, B., Albanese, C., Ahmed, F., Pixley, F., Lisanti, M.P., Segall, J.D., Condeelis, J., Joyce, D., Minden, A., Der, C.J Chan, A., Symons, M., and Pestell, R.G.. (2002). Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Mol Med, 7, 816-830.

Murphy, G.A., Graham, S.M., Reks, S.E., Vojtek, A., Rogers-Graham, K., Rogers-Graham, K., Kelley, G. and Der, C.J.  (2002). Involvement of phosphatidylinositol 3-kinase and phospholipase C epsilon, but not RalGDS, in TC21/R-Ras2-mediated transformation.  J Biol Chem, 277.  9966-9975.

Wolfman, J.C., Palmby, T., Der, C.J. and Wolfman, A.  (2002). Cellular N-Ras promotes cell survival by downregulation of JNK and p38.  Mol Cell Biol, 22, 1589-1606.

Shields, J.M., Mehta, H. and Der, C.J.  (2002). ERK and p38 mitogen-activated protein kinase cascades have opposing roles in Ras downregulation of tropomyosin.  Mol Cell Biol, 22, 2304-2317

Lambert, J.M., Karnoub, A., Graves, L.M., Campbell, S.L. and Der, C.J.  (2002). Rac activation of p70 S6 kinase is mediated by MLK-3 and is dispensable for Rac transformation.  J Biol Chem, 277, 4770-4777.

Shields, J., Rogers-Graham, K., Meeta, H. and Der, C.J.  (2002). Loss of transgelin and in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression by Raf-independent pathways.  J Biol Chem, 277, 9790-9799.

Booden, M.A., Der, C.J. and Campbell, S.L. (2002). Critical role of pleckstrin homology and cysteine-rich domain in Vav2 signaling and transformation.  Mol Cell Biol, 22, 2487-2497.

Solski, P.A., Helms, W., Keely, P.J., Su, L. and Der, C.J.  (2002). RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification.  Cell Growth Diff, 13, 363-373

Hamad, N.M., Elconin, J.H., Karnoub, A.E., J., Bai, W., Rich, J.N., Abraham, R.T., Der, C.J. and Counter, C.M.  (2002). Distinct requirements for Ras oncogenesis in human versus mouse cells.  Genes Dev, 16, 2045-2057.

Pruitt, K., Bilter, G.K., Westwick, J.K. and Der, C.J.  (2002). Opposing regulation and roles of p38 and JNK mitogen-activated protein kinases in Ras transformation.  J Biol Chem, 277, 31808-31817.

Reuther, G.W., Lambert, Q.T., Rebhun, J.F., Caligiuri, M.A., Quilliam, L.A., Der, C.J.  (2002). RasGRP4 is a novel ras activator isolated from acute myeloid leukemia.  J Biol Chem, 277, 30508-30514.

Lambert, J.M., Lambert, Q.T., Siderovski, D., Sondek, J. and Der, C.J.  (2002). Tiam1 is an effector for Ras activation of Rac.  Nat Cell Biol, 4, 621-625.

Snyder, J.T., Worthylake, D.K., Rossman, K.L., Betts, L., Pruitt, W.M., Siderovski, D.P., Der, C.J. and Sondek, J.  (2002).  Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.  Nat Struct Biol, 9, 468-475.

Booden MA, Siderovski DP, Der CJ (2002). Leukemia-associated Rho guanine nucleotide exchange factor promotes Galphaq-coupled activation of RhoA.  Mol Cell Biol, 22, 4053-4061.

Palmby, T.R, Abe, K. and Der, C.J.  (2002).  Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity.  J Biol Chem, 277, 39350-39359.

Dwivedi, P.P., Hii, C.S., Ferrante, A., Tan, J., Der, C.J., Omdahl, J.L., Morris, H.A. and May, B.K. (2002).  Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. specific functions for ERK1/ERK2 and ERK5.  J Biol Chem, 277, 29643-29653.

Arthur, W.T., Ellerbroek, S.M., Der, C.J., Burridge, K. and Wennerberg, K.  (2002).  XPLN, a guanine nucleotide exchange factor For RhoA and RhoB, but not RhoC .  J Biol Chem, 277, 42964-42972.

Wennerberg, K., Ellerbroek, S., Rong-Yu Liu, R.-Yu., Burridge, K. and Der, C.J.  (2002). RhoG signals in parallel with Rac1 and Cdc42.  J Biol Chem, 277, 47810-47817.

Hii, C.S., Costabile, M., Mayne, G.C., Der, C.J., Murray, A.W., Ferrante, A. Selective deficiency in protein kinase C isoenzyme expression and inadequacy in mitogen-activated protein kinase activation in cord blood T cells. Biochem J, 370, 497-503.


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