2005

Chenette, E.J., Abo, A. and Der, C.J.  (2005). Critical and distinct roles of amino and carboxyl terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase.  J Biol Chem, 280, 13784-13792.

Pruitt, K., Ülkü , A.S., Frantz, K., Rojas, R.J., Muniz-Medina, V.M., Rangnekar, V.M., Der, C.J. and Shields, J.M. (2005).  Ras mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.  J Biol Chem, 280, 23363-23370

Lim, K.H., Baines, A.T., Fiordalisi, J.J., Shipitsin, M., Feig, L.A., Cox, A.D., Der, C.J. and Counter, C.M.  (2005). Activation of RalA is critical for Ras-induced tumorigenesis of human cells.  Cancer Cell, 7, 533-545.

Brian C. Capell, Michael R. Erdos, James P. Madigan, James J. Fiordalisi, Renee Varga, Karen N. Conneely, Leslie B. Gordon, Channing J. Der, Adrienne D. Cox, and Francis S. Collins. (2005). Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.  Proc Natl Acad Sci USA, 36, 12879-12884.

Berzat, A.C., Buss, J.E., Chenette, E.J., Weinbaum, C.A., Shutes, A., Der, C.J., Minden, A. and Cox, A.D. (2005).  Transforming activity of the Rho family GTPase, Wrch-1, a Wnt-regulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif.  J. Biol. Chem., 280, 33055-33065.

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