2009

Yeh, J.J., Routh, E.D., Rubinas, T., Peacock, J., Martin, T.D., Shen, X.J., Sandler, R.S., Kim, H.J., Keku, T.O. Der, C.J. (2009). KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer. Mol Cancer Ther., 8, 834-843. PMCID:PMC2729756

Yang, X. Y., Guan, M., Vigil, D., Der, C.J., Lowy, D.R., Popescu. C. (2009). P120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth suppressing activities. Oncogene, 28, 1401-1409. PMCID:PMC2715999

Matsuo, Y., Campbell, P.M., Brekken, R.A., Sung, B., Ouellette, M.M., Fleming, J.B., Aggarwal, B.B., Der, C.J. and Guha, S.  (2009). K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through MAP kinase signaling pathways. Mol. Cancer Res., 7, 799-808. PMID:19509115

Cha, J.Y, Maddileti, S., Mitin, N. Harden, T.K., and Der, C.J. (2009). Aberrant receptor internalization and enhanced FRS2-dependent signaling contributes to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform. J. Biol. Chem., 284, 6227-6240. PMCID:PMC2649112

Willard, F.S., Willard, M.D., Kimple, A.J., Soundararajan, M.,Oestreich, E.A., Li, X., Sowa, N.A., Kimple, R.J., Doyle, D.A., Der, C.J., Zylka, M.J., Snider, W.D., and Siderovski, D.P. (2009). Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. PLoS ONE, 4, e4884. PMCID:PMC2655719

Hanker, A.B., Healy, K.D., Nichols, J. and Der, C.J. (2009). Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition. J Mol Signal.16, 4:5. PMCID:PMC2735739

Hanker, A.B., Mitin, N., Wilder, R.S., Henske, E.P., Tamanoi, F., Cox, A.D. and Der, C.J. (2009).  Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling. Oncogene, 29, 380-391. PMCID:PMC2809798

Madigan, J.P., Bodemann, B.O., Brady, D.C., Dewar, B.J., Keller, P.J., Leitges, M., Philips, M.R., Ridley, A.J., Der, C.J. and Cox, A.D. (2009).  Regulation of RND3 localization and function by PKCα-mediated phosphorylation.  Biochem. J., 424,153-161. PMCID:PMC2868966

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