2010

Lim, K.H., Brady, D.C., Kashatus, D.F., Ancrile, B.B., Der, C.J., Cox, A.D., and Counter, C.M. (2010) Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA. Mol Cell Biol., 30, 508-523. PMCID:PMC2798468

Gonzalez-Perez, V., Reiner, D.J., Alan, J.K., Mitchell, C., Edwards, L.J., Khazak, V., Der, C.J. and Cox, A.D. (2010) Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells. J Mol Signal, 23;5:2. PMCID:PMC2848644

Stevens, E.V., Wells, A., Shin, J. H., Liu, J., Der, C.J. and Schoenfisch, M.H. (2010) Nitric oxide-releasing silica nanoparticle inhibition of ovarian cancer cell growth. Mol. Pharmaceutics, 7:775-785. PMCID:PMC3569608

Kidd, A.R., 3rd, Snider, J.L., Martin, T.D., Graboski, S.F., Der, C.J., Cox, A.D. (2010). Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation. Int J Radiat Oncol Biol Phys., 78:205-212. PMCID:PMC2922474

Vigil, D., Williams, F., Yeh, J.J., Campbell, S.L. and Der, C.J. (2010). Aberrant overexpression of the RGL2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth. J. Biol. Chem., 285:34729-34740. PMCID:PMC2966088

Stratford, J.K., Bentrem, D.J. , Anderson, J.M., Volmar, K.A., Marron, J.S., Fan, C., Routh, E.D., Caskey, L.S., Samuel, J.C., Der, C.J., Thorne, L.B., Calvo, B.F., Kim, H.J., Talamonti, M.S., Iacobuzio-Donahue, C.A., Hollingsworth, M.A., Perou, C.M., Yeh, J.J. (2010). A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma. PLoS Medicine, 7(7):e1000307. PMCID:PMC2903589

Singh, A., Boyer JL, Der CJ, Zohn IE. (2010). Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Galphai, Galphaq and Rho-dependent signaling pathways. J Mol Signal., 5:11. PMCID:PMC2917412

Campbell, P.M., Boufaied, N., James J Fiordali, J.J., Cox, A.D., Falardeau, P., Der, C.J. and Gourdeau, H. (2010). TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling. J Mol Signal., 71:206-215. PMCID:PMC2990749

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